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Diindolylmethane (DIM)

Diindolylmethane (DIM) is a compound formed during the digestion of indole-3-carbinol, found in cruciferous vegetables like broccoli and cauliflower. It has garnered attention for its role in hormone metabolism, particularly estrogen balance.

In supplements, DIM is often used for hormonal support in both men and women. Athletes may benefit from DIM’s potential to support a favorable testosterone-to-estrogen ratio.

It acts by influencing estrogen metabolism pathways, promoting the formation of beneficial estrogen metabolites and possibly reducing the effects of more aggressive estrogenic compounds.

Synonyms:

3,3′-Diindolylmethane

Benefits:

  • Supports healthy estrogen metabolism
  • May aid in hormonal balance
  • Potential support for body composition management

Sources:

Derived from cruciferous vegetables; concentrated in supplement form.

Observations:

Often found in hormone support or detox supplements. Usually well-tolerated, but high doses may lead to mild gastrointestinal discomfort.

Areas of Study Related:

Nutritional Biochemistry, Endocrinology, Oncology Research.